Annals of Oncology

In this issue:

In this issue: Contents of the next issue
Ann Oncol 7: 1.
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News:

Steven Dickman

Bloom's syndrome enzyme leads to a new cancer mechanism
Ann Oncol 7: 2.
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European Drug Agency: Not yet ready for oncology
Ann Oncol 7: 2-3.
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Should industry help pay for clinical trials?
Ann Oncol 7: 3.
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Big business in favour of legalising drugs
Ann Oncol 7: 3.
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Israeli-Arabic cooperation in oncology under Euro-American auspices
Ann Oncol 7: 3-5.
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Perhaps not everyone knows that...
Ann Oncol 7: 5-6.
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Book reviews:

J.-P. Armand

Book review
Ann Oncol 7: 6.
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C. Sessa

Book review
Ann Oncol 7: 8.
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Editorial:

F. Cavalli

Annals of Oncology continues to expand and improve
Ann Oncol 7: 7.
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Special articles:

S. B. Kaye

Ovarian cancer, from the laboratory to the clinic: Challenges for the future
Ann Oncol 7: 9-13.
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Review:

E. E. Vokes and I. Athanasiadis

Chemotherapy for squamous cell carcinoma of head and neck: The future is now
Ann Oncol 7: 15-29.
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Rapid publication:

C. Bokemeyer, J. Beyer, B. Metzner, U. Rüther, A. Harstrick, L. Weißbach, U. Köhrmann, W. Verbeek, and H.-J. Schmoll

Phase II study of paclitaxel in patients with relapsed or cisplatin-refractory testicular cancer
Ann Oncol 7: 31-34.
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Original articles:

A. H. Honkoop, K. Hoekman, J. Wagstaff, E. Boven, C. J. van Groeningen, G. Giaccone, J. B. Vermorken, and H. M. Pinedo

Dose-intensive chemotherapy with doxorubicin, cyclophosphamide and GM-CSF fails to improve survival of metastatic breast cancer patients
Ann Oncol 7: 35-39.
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J. R. Zalcberg, J. Siderov, and J. Simes

The role of 5-fluorouracil dose in the adjuvant therapy of colorectal cancer
Ann Oncol 7: 41-46.
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M. P. N. Findlay, F. Raynaud, D. Cunningham, A. Iveson, D. J. Collins, and M. O. Leach

Measurement of plasma 5-fluorouracil by high-performance liquid chromatography with comparison of results to tissue drug levels observed using in vivo 19F magnetic resonance spectroscopy in patients on a protracted venous infusion with or without interferon-
Ann Oncol 7: 47-53.
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H. Wilke, U. Klaassen, W. Achterrath, M. Losch, U. Vanhoefer, J. Hayungs, A. Harstrick, M. Stahl, W. Eberhardt, R. Becher, and S. Seeber

Phase I/II study with a weekly 24-hour infusion of 5-fluorouracil plus high-dose folinic acid (HD-FU/FA) in intensively pretreated patients with metastatic breast cancer
Ann Oncol 7: 55-58.
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M. H. Huber, J. S. Lee, R. A. Newman, F. V. Fossella, M. Wester, W. Ki Hong, and S. M. Lippman

A phase I investigation of the sequential use of methotrexate and paclitaxel with and without G-CSF for the treatment of solid tumors
Ann Oncol 7: 59-63.
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K. Buser, M. Bacchi, A. Goldhirsch, R. Greiner, P. Diener, C. Sessa, W. F. Jungi, M. Forni, S. Leyvraz, V. Engeler, and Swiss Group of Clinical Cancer Research (SAKK)

Treatment of ovarian cancer with surgery, short-course chemotherapy and whole abdominal radiation
Ann Oncol 7: 65-70.
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W. H. Koo and P. T. Ang

Role of maintenance oral dexamethasone in prophylaxis of delayed emesis caused by moderately emetogenic chemotherapy
Ann Oncol 7: 71-74.
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K. Nooter, F. T. Bosman, H. Burger, K. E. van Wingerden, M. J. Flens, R. J. Scheper, R. G. Oostrum, A. W. M. Boersma, A. van der Gaast, and G. Stoter

Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer
Ann Oncol 7: 75-81.
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K. Mross, J. Reifke, P. Bewermeier, W. Krüger, D. K. Hossfeld, and A. Zander

The pharmacokinetics and toxicity of two application schedules with high-dose VP-16 in patients receiving an allogeneic bone marrow transplantation
Ann Oncol 7: 83-88.
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Clinical case:

J. L. Craze and J. Pritchard

Langerhans' cell histiocytosis: A case history
Ann Oncol 7: 89-94.
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Short report:

D. Machover, E. Diaz-Rubio, A. de Gramont, A. Schif, J.-J. Gastiaburu, S. Brienza, M. Itzhaki, G. Metzger, D. N'Daw, J. Vignoud, A. Abad, E. François, E. Gamelin, M. Marty, J. Sastre, J.-F. Seitz, and M. Ychou

Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines
Ann Oncol 7: 95-98.
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G. Bisagni, G. Cocconi, F. Scaglione, F. Fraschini, Ch. Pfister, and P. F. Trunet

Letrozole, a new oral non-steroidal aromastase inhibitor in treating postmenopausal patients with advanced breast cancer. A pilot study
Ann Oncol 7: 99-102.
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Letters to the editor:

R. Dukoff, I. D. Horak, R. Hassan, and D. L. Rosenstein

Akathisia associated with prochiorperazine as an antiemetic: A case report
Ann Oncol 7: 103.
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A. M. Westermann, W. W. ten Bokkel Huinink, and S. Rodenhuis

Successful docetaxel rechallenge with cromoglycate after major sensitivity reactions
Ann Oncol 7: 104.
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Instructions to authors:

Instructions to authors
Ann Oncol 7: 105-106.
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Classified advertisements from ESMO members and meeting announcements
Ann Oncol 7: 108.
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ESMO applications for membership
Ann Oncol 7: 109.
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Rapid Science Publishers
Ann Oncol 7: 110.
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Kluwer Academic Publishers
Ann Oncol 7: 111.
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Bristol-Myers Squibb
Ann Oncol 7: 112.
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Kluwer Academic Publishers
Ann Oncol 7: 112.
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