Annals of Oncology

Editorials:

D. J. Kerr and N. B. La Thangue

Signal transduction blockade and cancer: combination therapy or multi-targeted inhibitors?
Ann Oncol 15: 1727-1729; doi:10.1093/annonc/mdh480
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Reviews:

L. Pusztai and K. R. Hess

Clinical trial design for microarray predictive marker discovery and assessment
Ann Oncol 15: 1731-1737; doi:10.1093/annonc/mdh466
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J. S. Tobias

Recent advances in endocrine therapy for postmenopausal women with early breast cancer: implications for treatment and prevention
Ann Oncol 15: 1738-1747; doi:10.1093/annonc/mdh485
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Original articles:

Breast cancer:

International Breast Cancer Study Group

Toremifene and tamoxifen are equally effective for early-stage breast cancer: first results of International Breast Cancer Study Group Trials 12-93 and 14-93
Ann Oncol 15: 1749-1759; doi:10.1093/annonc/mdh463
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D. Hess, B. Thürlimann, O. Pagani, S. Aebi, D. Rauch, P. Ballabeni, B. Rufener, M. Castiglione-Gertsch, and A. Goldhirsch On behalf of the Swiss Group of Clinical Cancer Research

Capecitabine and vinorelbine in elderly patients (65 years) with metastatic breast cancer: a phase I trial (SAKK 25/99)
Ann Oncol 15: 1760-1765; doi:10.1093/annonc/mdh467
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Gastrointestinal tumors:

G. Masi, G. Allegrini, S. Cupini, L. Marcucci, E. Cerri, I. Brunetti, E. Fontana, S. Ricci, M. Andreuccetti, and A. Falcone

First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule
Ann Oncol 15: 1766-1772; doi:10.1093/annonc/mdh470
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C. Pozzo, C. Barone, J. Szanto, E. Padi, C. Peschel, J. Bükki, V. Gorbunova, V. Valvere, J. Zaluski, M. Biakhov, E. Zuber, C. Jacques, and R. Bugat

Irinotecan in combination with 5-fluorouracil and folinic acid or with cisplatin in patients with advanced gastric or esophageal-gastric junction adenocarcinoma: results of a randomized phase II study
Ann Oncol 15: 1773-1781; doi:10.1093/annonc/mdh473
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Lung cancer:

K. Hotta, K. Matsuo, H. Ueoka, K. Kiura, M. Tabata, and M. Tanimoto

Addition of platinum compounds to a new agent in patients with advanced non-small-cell lung cancer: a literature based meta-analysis of randomised trials
Ann Oncol 15: 1782-1789; doi:10.1093/annonc/mdh476
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Hematologic malignancies:

N. Mounier, C. Gisselbrecht, J. Brière, C. Haioun, P. Feugier, F. Offner, C. Recher, A. Stamatoullas, F. Morschhauser, M. Macro, C. Thieblemont, A. Sonet, B. Fabiani, and F. Reyes On behalf of the Groupe d'Etude des Lymphomes de l'Adulte

All aggressive lymphoma subtypes do not share similar outcome after front-line autotransplantation: a matched-control analysis by the Groupe d'Etude des Lymphomes de l'Adulte (GELA)
Ann Oncol 15: 1790-1797; doi:10.1093/annonc/mdh471
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A. Rueda Domínguez, A. Márquez, J. Gumá, M. Llanos, J. Herrero, M. A. de las Nieves, J. Miramón, and E. Alba

Treatment of stage I and II Hodgkin's lymphoma with ABVD chemotherapy: results after 7 years of a prospective study
Ann Oncol 15: 1798-1804; doi:10.1093/annonc/mdh465
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G. Toffoli, G. Corona, G. Cattarossi, M. Boiocchi, G. Di Gennaro, U. Tirelli, and E. Vaccher

Effect of highly active antiretroviral therapy (HAART) on pharmacokinetics and pharmacodynamics of doxorubicin in patients with HIV-associated non-Hodgkin's lymphoma
Ann Oncol 15: 1805-1809; doi:10.1093/annonc/mdh464
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P. Mollee, C. Arthur, T. Hughes, H. Januszewicz, A. Grigg, K. Bradstock, M. Wolf, J. Gibson, A. P. Schwarer, A. Spencer, P. Browett, T. Hawkins, M. Seldon, R. Herrmann, A. Watson, J. F. Seymour, N. Martin, S. Shina, C. Low, S. Wright, R. Rodwell, J. Coulston, J. Morton, H. Blacklock, D. Taylor, and K. M. Taylor

Interferon--2b and oral cytarabine ocfosfate for newly diagnosed chronic myeloid leukaemia
Ann Oncol 15: 1810-1815; doi:10.1093/annonc/mdh468
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Phase I and pharmacokinetics:

P. Schöffski, S. Riggert, P. Fumoleau, M. Campone, O. Bolte, S. Marreaud, D. Lacombe, B. Baron, M. Herold, H. Zwierzina, K. Wilhelm-Ogunbiyi, H. Lentzen, and C. Twelves

Phase I trial of intravenous aviscumine (rViscumin) in patients with solid tumors: a study of the European Organization for Research and Treatment of Cancer New Drug Development Group
Ann Oncol 15: 1816-1824; doi:10.1093/annonc/mdh469
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J. S. de Bono, S. Y. Rha, J. Stephenson, B. C. Schultes, P. Monroe, G. S. Eckhardt, L. A. Hammond, T. L. Whiteside, C. F. Nicodemus, J. M. Cermak, E. K. Rowinsky, and A. W. Tolcher

Phase I trial of a murine antibody to MUC1 in patients with metastatic cancer: evidence for the activation of humoral and cellular antitumor immunity
Ann Oncol 15: 1825-1833; doi:10.1093/annonc/mdh472
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Epidemiology:

J. Lorenzo Bermejo and K. Hemminki

Risk of cancer at sites other than the breast in Swedish families eligible for BRCA1 or BRCA2 mutation testing
Ann Oncol 15: 1834-1841; doi:10.1093/annonc/mdh474
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F. Chiesa, N. Tradati, L. Calabrese, B. Gibelli, G. Giugliano, G. Paganelli, C. De Cicco, C. Grana, G. Tosi, E. DeFiori, G. Cammarano, A. Cusati, and S. Zurrida

Thyroid disease in northern Italian children born around the time of the Chernobyl nuclear accident
Ann Oncol 15: 1842-1846; doi:10.1093/annonc/mdh477
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Letters to the Editor:

G. Ferretti, M. C. Petti, P. Carlini, M. Zeuli, A. Picardi, G. Meloni, E. Bria, P. Papaldo, A. Fabi, and F. Cognetti

Zoledronic acid-associated thrombotic thrombocytopenic purpura
Ann Oncol 15: 1847-1848; doi:10.1093/annonc/mdh478
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D. Singh, N. S. Khaira, and J. S. Sekhon

Symptomatic hypocalcaemia after treatment with zoledronic acid in a patient with multiple myeloma
Ann Oncol 15: 1848; doi:10.1093/annonc/mdh479
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G. Utkan, A. Büyükçelik, and B. Yalçin

Solid tumors in patients treated for Hodgkin's disease
Ann Oncol 15: 1848-1849; doi:10.1093/annonc/mdh481
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M. R. Hussein, T. M. Al-Sabae, and M. N. Georgis

Analysis of Bcl-2 and p53 protein expression in non-Hodgkin's lymphoma
Ann Oncol 15: 1849-1850; doi:10.1093/annonc/mdh483
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N. Fazio, T. De Pas, F. de Braud, L. Spaggiari, G. Mazzarol, R. Biffi, B. Andreoni, M. Zampino, G. Curigliano, K. Lorizzo, G. Di Meglio, and A. Goldhirsch

CDX-2 should be included in the work-up of patients with lung metastases from unknown primary
Ann Oncol 15: 1850; doi:10.1093/annonc/mdh482
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Book reviews:

D. Schrijvers

Oxford Textbook of Palliative Medicine, 3rd edition
Ann Oncol 15: 1851; doi:10.1093/annonc/mdh475
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C. J. A. Punt

Progress in Oncology 2004
Ann Oncol 15: 1851; doi:10.1093/annonc/mdh484
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