Annals of Oncology

Editorials:

D. Kerr

A little citadel of light in a malignant sea of darkness
Ann Oncol 15: 1-2; doi:10.1093/annonc/mdh034
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F. Andre, T. Le Chevalier, and J. C. Soria

Her2-neu: a target in lung cancer?
Ann Oncol 15: 3-4; doi:10.1093/annonc/mdh033
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Peter Boyle, Jean-Francois Doré, Phillipe Autier, and Ulrik Ringborg

Cancer of the skin: a forgotten problem in Europe
Ann Oncol 15: 5-6; doi:10.1093/annonc/mdh032
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Reviews:

L. Licitra and J. B. Vermorken

Is there still a role for neoadjuvant chemotherapy in head and neck cancer?
Ann Oncol 15: 7-11; doi:10.1093/annonc/mdh001
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S. A. Pileri, P. L. Zinzani, P. Went, A. Pileri, Jr, and M. Bendandi

Indolent lymphoma: the pathologist’s viewpoint
Ann Oncol 15: 12-18; doi:10.1093/annonc/mdh002
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Original articles:

Lung cancer:

U. Gatzemeier, G. Groth, C. Butts, N. Van Zandwijk, F. Shepherd, A. Ardizzoni, C. Barton, P. Ghahramani, and V. Hirsh

Randomized phase II trial of gemcitabine–cisplatin with or without trastuzumab in HER2-positive non-small-cell lung cancer
Ann Oncol 15: 19-27; doi:10.1093/annonc/mdh031
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G. Selvaggi, S. Novello, V. Torri, E. Leonardo, P. De Giuli, P. Borasio, C. Mossetti, F. Ardissone, P. Lausi, and G. V. Scagliotti

Epidermal growth factor receptor overexpression correlates with a poor prognosis in completely resected non-small-cell lung cancer
Ann Oncol 15: 28-32; doi:10.1093/annonc/mdh011
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A. Santoro, R. Cavina, F. Latteri, P. A. Zucali, V. Ginanni, E. Campagnoli, B. Ferrari, E. Morenghi, V. Pedicini, M. Roncalli, M. Alloisio, G. Ravasi, and H. J. Soto Parra

Activity of a specific inhibitor, gefitinib (Iressa^TM, ZD1839), of epidermal growth factor receptor in refractory non-small-cell lung cancer
Ann Oncol 15: 33-37; doi:10.1093/annonc/mdh010
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E. Quoix, B. Lebeau, A. Depierre, A. Ducolone, D. Moro-Sibilot, B. Milleron, J. L. Breton, E. Lemarie, J. L. Pujol, J. M. Brechot, G. Zalcman, D. Debieuvre, F. Vaylet, A. Vergnenegre, and P. Clouet

Randomised, multicentre phase II study assessing two doses of docetaxel (75 or 100 mg/m²) as second-line monotherapy for non-small-cell lung cancer
Ann Oncol 15: 38-44; doi:10.1093/annonc/mdh005
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Y. Ohe, S. Niho, R. Kakinuma, K. Kubota, H. Ohmatsu, K. Goto, H. Nokihara, H. Kunitoh, N. Saijo, H. Aono, K. Watanabe, M. Tango, A. Yokoyama, and Y. Nishiwaki

A phase II study of cisplatin and docetaxel administered as three consecutive weekly infusions for advanced non-small-cell lung cancer in elderly patients
Ann Oncol 15: 45-50; doi:10.1093/annonc/mdh015
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A. Inoue, Y. Saijo, T. Kikuchi, K. Gomi, T. Suzuki, M. Maemondo, M. Miki, T. Sato, and T. Nukiwa

Pharmacokinetic analysis of combination chemotherapy with carboplatin and etoposide in small-cell lung cancer patients undergoing hemodialysis
Ann Oncol 15: 51-54; doi:10.1093/annonc/mdh008
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Gastrointestinal tumors:

O. Belvedere, F. Puglisi, C. Di Loreto, P. Cataldi, A. Guglielmi, C. Aschele, and A. Sobrero

Lack of correlation between immunohistochemical expression of E2F-1, thymidylate synthase expression and clinical response to 5-fluorouracil in advanced colorectal cancer
Ann Oncol 15: 55-58; doi:10.1093/annonc/mdh018
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J. M. G. H. van Riel, C. J. van Groeningen, J. de Greve, G. Gruia, H. M. Pinedo, and G. Giaccone

Continuous infusion of hepatic arterial irinotecan in pretreated patients with colorectal cancer metastatic to the liver
Ann Oncol 15: 59-63; doi:10.1093/annonc/mdh022
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L. Assersohn, G. Brown, D. Cunningham, C. Ward, J. Oates, J. S. Waters, M. E. Hill, and A. R. Norman

Phase II study of irinotecan and 5-fluorouracil/leucovorin in patients with primary refractory or relapsed advanced oesophageal and gastric carcinoma
Ann Oncol 15: 64-69; doi:10.1093/annonc/mdh007
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P. Ghiorzo, L. Pastorino, L. Bonelli, R. Cusano, A. Nicora, S. Zupo, P. Queirolo, M. Sertoli, V. Pugliese, and G. Bianchi-Scarrà

INK4/ARF germline alterations in pancreatic cancer patients
Ann Oncol 15: 70-78; doi:10.1093/annonc/mdg498
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Breast cancer:

C. Pico, M. Martin, C. Jara, A. Barnadas, A. Pelegri, A. Balil, C. Camps, A. Frau, A. Rodriguez-Lescure, J. M. Lopez-Vega, J. de la Haba, A. Tres, I. Alvarez, E. Alba, A. Arcusa, A. Oltra, N. Batista, T. Checa, R. Perez-Carrion, and J. Curto

Epirubicin–cyclophosphamide adjuvant chemotherapy plus tamoxifen administered concurrently versus sequentially: randomized phase III trial in postmenopausal node-positive breast cancer patients. A GEICAM 9401 study
Ann Oncol 15: 79-87; doi:10.1093/annonc/mdh016
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R. Rönkä, K. v. Smitten, H. Sintonen, T. Kotomäki, L. Krogerus, E. Leppänen, and M. Leidenius

The impact of sentinel node biopsy and axillary staging strategy on hospital costs
Ann Oncol 15: 88-94; doi:10.1093/annonc/mdh019
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A. Alexopoulos, D. Tryfonopoulos, M. V. Karamouzis, G. Gerasimidis, I. Karydas, K. Kandilis, J. Stavrakakis, H. Stavrinides, C. Georganta, A. Ardavanis, and G. Rigatos

Evidence for in vivo synergism between docetaxel and gemcitabine in patients with metastatic breast cancer
Ann Oncol 15: 95-99; doi:10.1093/annonc/mdh028
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Gynecologic tumors:

W. ten Bokkel Huinink, S. R. Lane, and G. A. Ross

Long-term survival in a phase III, randomised study of topotecan versus paclitaxel in advanced epithelial ovarian carcinoma
Ann Oncol 15: 100-103; doi:10.1093/annonc/mdh025
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S. Camilleri-Broët, A. C. Hardy-Bessard, A. Le Tourneau, D. Paraiso, O. Levrel, B. Leduc, S. Bain, H. Orfeuvre, J. Audouin, and E. Pujade-Lauraine

HER-2 overexpression is an independent marker of poor prognosis of advanced primary ovarian carcinoma: a multicenter study of the GINECO group
Ann Oncol 15: 104-112; doi:10.1093/annonc/mdh021
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Head and neck cancer:

P. Comoli, R. De Palma, S. Siena, A. Nocera, S. Basso, F. Del Galdo, R. Schiavo, O. Carminati, A. Tagliamacco, G. F. Abbate, F. Locatelli, R. Maccario, and P. Pedrazzoli

Adoptive transfer of allogeneic Epstein–Barr virus (EBV)-specific cytotoxic T cells with in vitro antitumor activity boosts LMP2-specific immune response in a patient with EBV-related nasopharyngeal carcinoma
Ann Oncol 15: 113-117; doi:10.1093/annonc/mdh027
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A. Alidina, A. Gaffar, F. Hussain, M. Islam, I. Vaziri, I. Burney, A. Valimohd, and W. Jafri

Survival data and prognostic factors seen in Pakistani patients with esophageal cancer
Ann Oncol 15: 118-122; doi:10.1093/annonc/mdh014
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Hematologic malignancies:

A. Levis, A. P. Anselmo, A. Ambrosetti, F. Adamo, M. Bertini, E. Cavalieri, P. Gavarotti, A. Genua, M. Liberati, V. Pavone, D. Pietrasanta, M. M. Ricetti, D. R. Scalabrini, F. Salvi, U. Vitolo, E. Angelucci, M. Boccadoro, E. Gallo, and F. Mandelli

VEPEMB in elderly Hodgkin’s lymphoma patients. Results from an Intergruppo Italiano Linfomi (IIL) study
Ann Oncol 15: 123-128; doi:10.1093/annonc/mdh012
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P. Feugier, J. M. Virion, H. Tilly, C. Haioun, G. Marit, M. Macro, D. Bordessoule, C. Recher, M. Blanc, T. Molina, P. Lederlin, and B. Coiffier

Incidence and risk factors for central nervous system occurrence in elderly patients with diffuse large-B-cell lymphoma: influence of rituximab
Ann Oncol 15: 129-133; doi:10.1093/annonc/mdh013
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K. Zervas, M. A. Dimopoulos, E. Hatzicharissi, A. Anagnostopoulos, M. Papaioannou, Ch. Mitsouli, P. Panagiotidis, J. Korantzis, M. Tzilianos, and A. Maniatis

Primary treatment of multiple myeloma with thalidomide, vincristine, liposomal doxorubicin and dexamethasone (T-VAD doxil): a phase II multicenter study
Ann Oncol 15: 134-138; doi:10.1093/annonc/mdh026
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Miscellaneous tumors:

L. V. Beerepoot, N. Mehra, J. S. P. Vermaat, B. A. Zonnenberg, M. F. G. B. Gebbink, and E. E. Voest

Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients
Ann Oncol 15: 139-145; doi:10.1093/annonc/mdh017
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N. Germann, F. Goffinet, and F. Goldwasser

Anthracyclines during pregnancy: embryo–fetal outcome in 160 patients
Ann Oncol 15: 146-150; doi:10.1093/annonc/mdh009
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M. Serra, G. Reverter-Branchat, D. Maurici, S. Benini, J.-N. Shen, T. Chano, C.-M. Hattinger, M.-C. Manara, M. Pasello, K. Scotlandi, and P. Picci

Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells
Ann Oncol 15: 151-160; doi:10.1093/annonc/mdh004
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K. Vera, L. Djafari, S. Faivre, J.-S. Guillamo, K. Djazouli, M. Osorio, F. Parker, C. Cioloca, B. Abdulkarim, J.-P. Armand, and E. Raymond

Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors
Ann Oncol 15: 161-171; doi:10.1093/annonc/mdh003
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Letters to the Editor:

T. Kurata, K. Tamura, H. Kaneda, T. Nogami, H. Uejima, G. Asai, K. Nakagawa, and M. Fukuoka

Effect of re-treatment with gefitinib (‘Iressa’, ZD1839) after acquisition of resistance
Ann Oncol 15: 173-174; doi:10.1093/annonc/mdh006
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B. Isik and K. Altundag

Vinorelbine, methotrexate and fluorouracil (VMF) as first-line therapy in metastatic breast cancer: significance of the time between initiation of adjuvant therapy and of therapy for metastatic breast cancer
Ann Oncol 15: 175; doi:10.1093/annonc/mdh023
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C. Blomqvist

Reply to "Letter to the Editor on ‘Vinorelbine, methotrexate and fluorouracil (VMF) as first line therapy in metastatic breast cancer: a randomised phase II trial’", by B. Isik and K. Altundag (Ann Oncol 2004; 15: 175)
Ann Oncol 15: 175; doi:10.1093/annonc/mdh024
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H. van den Berg and A. M. Reintsema

Renal tubular damage in rasburicase: risks of alkalinisation
Ann Oncol 15: 175-176; doi:10.1093/annonc/mdh029
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B. Kasper, T. Moehler, K. Neben, A. D. Ho, and H. Goldschmidt

Combination therapy of Thalidomide and Peginterferon in patients with progressive multiple myeloma
Ann Oncol 15: 176-177; doi:10.1093/annonc/mdh030
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Book reviews:

H. C. Schouten

M. J. Laughlin and H. M. Lazarus (eds). Allogeneic Stem Cell Transplantation; Clinical Research and Practice
Ann Oncol 15: 179; doi:10.1093/annonc/mdh020
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Corrigenda:

J.-J. Body, I. J. Diel, M. R. Lichinitser, E. D. Kreuser, W. Dornoff, V. A. Gorbunova, M. Budde, and B. Bergström

Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases ;
Ann Oncol 15: 180; doi:10.1093/annonc/mdh035
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