Annals of Oncology

Editorials:

D. Schrijvers, J. B. Vermorken, C. Bokemeyer, and H. Ludwig

Continuing medical education: a must for every medical oncologist
Ann Oncol 14: 1455-1459; doi:10.1093/annonc/mdg421
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H. Joensuu

Primary chemotherapy of breast cancer followed by perioperative chemotherapy: feasible, but are there clinical benefits?
Ann Oncol 14: 1460-1462; doi:10.1093/annonc/mdg423
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Reviews:

M.-F. Yuen and C.-L. Lai

Screening for hepatocellular carcinoma: survival benefit and cost-effectiveness
Ann Oncol 14: 1463-1467; doi:10.1093/annonc/mdg400
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D. Santini, U. Vespasiani Gentilucci, B. Vincenzi, A. Picardi, F. Vasaturo, A. La Cesa, N. Onori, S. Scarpa, and G. Tonini

The antineoplastic role of bisphosphonates: from basic research to clinical evidence
Ann Oncol 14: 1468-1476; doi:10.1093/annonc/mdg401
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Original articles:

Breast cancer:

M. Colleoni, G. Curigliano, I. Minchella, G. Peruzzotti, F. Nolè, G. Mazzarol, G. Renne, L. Orlando, A. Rocca, P. Veronesi, M. Intra, G. Viale, M. T. Sandri, G. Severi, and A. Goldhirsch

Preoperative and perioperative chemotherapy with 5-fluorouracil as continuous infusion in operable breast cancer expressing a high proliferation fraction: cytotoxic treatment during the surgical phase
Ann Oncol 14: 1477-1483; doi:10.1093/annonc/mdg411
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E. Biganzoli, P. Boracchi, D. Coradini, M. Grazia Daidone, and E. Marubini

Prognosis in node-negative primary breast cancer: a neural network analysis of risk profiles using routinely assessed factors
Ann Oncol 14: 1484-1493; doi:10.1093/annonc/mdg422
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Gynecologic malignancies:

G. B. Kristensen, W. Kildal, V. M. Abeler, J. Kaern, I. Vergote, C. G. Tropé, and H. E. Danielsen

Large-scale genomic instability predicts long-term outcome for women with invasive stage I ovarian cancer
Ann Oncol 14: 1494-1500; doi:10.1093/annonc/mdg403
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J. Sehouli, A. Mustea, D. Koensgen, F. C.-K. Chen, and W. Lichtenegger

Interleukin-1 receptor antagonist gene polymorphism is associated with increased risk of epithelial ovarian cancer
Ann Oncol 14: 1501-1504; doi:10.1093/annonc/mdg413
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Y. Shinyo, J. Kodama, A. Hongo, M. Yoshinouchi, and Y. Hiramatsu

Heparanase expression is an independent prognostic factor in patients with invasive cervical cancer
Ann Oncol 14: 1505-1510; doi:10.1093/annonc/mdg407
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P. Morice, P. Piovesan, A. Rey, D. Atallah, C. Haie-Meder, P. Pautier, L. Sideris, C. Pomel, P. Duvillard, and D. Castaigne

Prognostic value of lymphovascular space invasion determined with hematoxylin–eosin staining in early stage cervical carcinoma: results of a multivariate analysis
Ann Oncol 14: 1511-1517; doi:10.1093/annonc/mdg412
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Urogenital tumors:

O. Smaletz, M. Galsky, H. I. Scher, A. DeLaCruz, S. F. Slovin, M. J. Morris, D. B. Solit, U. Davar, L. Schwartz, and W. K. Kelly

Pilot study of epothilone B analog (BMS-247550) and estramustine phosphate in patients with progressive metastatic prostate cancer following castration
Ann Oncol 14: 1518-1524; doi:10.1093/annonc/mdg415
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A. Aigner, P. Brachmann, J. Beyer, R. Jäger, D. Raulais, M. Vigny, A. Neubauer, A. Heidenreich, S. Weinknecht, F. Czubayko, and G. Zugmaier

Marked increase of the growth factors pleiotrophin and fibroblast growth factor-2 in serum of testicular cancer patients
Ann Oncol 14: 1525-1529; doi:10.1093/annonc/mdg416
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Gastrointestinal tumors:

M. Colombino, A. Cossu, A. Arba, A. Manca, A. Curci, A. Avallone, G. Comella, G. Botti, F. Scintu, M. Amoruso, D. D’Abbicco, M. R. d’Agnessa, A. Spanu, F. Tanda, and G. Palmieri

Microsatellite instability and mutation analysis among southern Italian patients with colorectal carcinoma: detection of different alterations accounting for MLH1 and MSH2 inactivation in familial cases
Ann Oncol 14: 1530-1536; doi:10.1093/annonc/mdg402
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L. Zelek, R. Bugat, D. Cherqui, G. Ganem, P. Valleur, R. Guimbaud, O. Dupuis, T. Aziza, P. L. Fagniez, J. Auroux, H. Kobeiter, C. Tayar, A. C. Braud, E. Haddad, A. Piolot, M. Buyse, and P. Piedbois

Multimodal therapy with intravenous biweekly leucovorin, 5-fluorouracil and irinotecan combined with hepatic arterial infusion pirarubicin in non-resectable hepatic metastases from colorectal cancer (a European Association for Research in Oncology trial)
Ann Oncol 14: 1537-1542; doi:10.1093/annonc/mdg404
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E. Bajetta, L. Celio, R. Buzzoni, L. Ferrari, A. Marchianò, A. Martinetti, R. Longarini, C. Becerra, C. Ilardi, and W. John

Phase II study of pemetrexed disodium (Alimta^®) administered with oral folic acid in patients with advanced gastric cancer
Ann Oncol 14: 1543-1548; doi:10.1093/annonc/mdg406
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Lung cancer:

E. Felip, R. Rosell, M. Domine, L. Santomé, P. Garrido, A. Font, A. Carrato, J. Terrasa, C. Vadell, J. M. Mañe, and J. Baselga

Sequential dose-dense paclitaxel followed by topotecan in untreated extensive-stage small-cell lung cancer: a Spanish Lung Cancer Group phase II study
Ann Oncol 14: 1549-1554; doi:10.1093/annonc/mdg405
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Hematologic malignancies:

H. A. Leitch, R. D. Gascoyne, M. Chhanabhai, N. J. Voss, R. Klasa, and J. M. Connors

Limited-stage mantle-cell lymphoma
Ann Oncol 14: 1555-1561; doi:10.1093/annonc/mdg414
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P. Hartmann, U. Rehwald, B. Salzberger, C. Franzen, M. Sieber, A. Wöhrmann, and V. Diehl

BEACOPP therapeutic regimen for patients with Hodgkin’s disease and HIV infection
Ann Oncol 14: 1562-1569; doi:10.1093/annonc/mdg408
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Supportive care:

R. Gralla, M. Lichinitser, S. Van der Vegt, H. Sleeboom, J. Mezger, C. Peschel, G. Tonini, R. Labianca, A. Macciocchi, and M. Aapro

Palonosetron improves prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy: results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetron
Ann Oncol 14: 1570-1577; doi:10.1093/annonc/mdg417
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Phase I and pharmacokinetics:

X. Pivot, E. Chamorey, E. Guardiola, N. Magné, A. Thyss, J. Otto, B. Giroux, Z. Mouri, M. Schneider, and G. Milano

Phase I and pharmacokinetic study of the association of capecitabine–cisplatin in head and neck cancer patients
Ann Oncol 14: 1578-1586; doi:10.1093/annonc/mdg410
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Letters to the Editor:

L. Repetto, O. Vannozzi, A. Hazini, A. Sestini, M. Pietropaolo, and R. Rosso

Anastrozole and quinapril can be safely coadministered to elderly women with breast cancer and hypertension: a pharmacokinetic study
Ann Oncol 14: 1587-1588; doi:10.1093/annonc/mdg409
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U. De Giorgi, G. Rosti, M. Monti, G. L. Frassineti, and M. Marangolo

Onycholysis secondary to multiple paclitaxel 1-hour infusions: possible role for its vehicle (Cremophor EL)
Ann Oncol 14: 1588-1589; doi:10.1093/annonc/mdg419
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A. Berruti, A. Saini, G. Gorzegno, M. Tampellini, P. Borasio, and L. Dogliotti

Durable complete remission after weekly docetaxel administration in a patient with mediastinal non-seminomatous germ-cell tumor refractory to cisplatin-based chemotherapy
Ann Oncol 14: 1589-1590; doi:10.1093/annonc/mdg420
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Book reviews:

M. Castiglione-Gertsch

Z. Rayter, J. Mansi (eds). Medical Therapy of Breast Cancer
Ann Oncol 14: 1591; doi:10.1093/annonc/mdg418
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