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Annals of Oncology Advance Access published online on August 22, 2008
Annals of Oncology, doi:10.1093/annonc/mdn566
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© The Author 2008. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

letter to the editor

Acute exacerbation of hemorrhagic rectocolitis during antiangiogenic therapy with sunitinib and sorafenib

The first 10% of the full text of this article appears below.

Angiogenic inhibitors (AIs) have been found to increase survival and are approved in advanced renal cell carcinoma [1, 2]. Consequently, most of these patients will routinely receive these two tyrosine kinase inhibitors, sorafenib and sunitinib.

The toxicity of these agents requires a deeper mechanistic understanding so that prevention and . . . [Full Text of this Article]

Y. Loriot*, P. Boudou-Rouquette, B. Billemont, S. Ropert and F. Goldwasser

Department of Oncology, Faculty of Medicine, Paris Public Assistance Hospital, Cochin Hospital, Paris V University, Paris, France

* (E-mail: y.loriot@voila.fr)


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