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Annals of Oncology Advance Access published online on December 20, 2007

Annals of Oncology, doi:10.1093/annonc/mdm568
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© 2007 European Society for Medical Oncology. For Permissions, please email: journals.permissions@oxfordjournals.org

letter to the editor

Prolonged control of progressive castration-resistant metastatic prostate cancer with testosterone replacement therapy: the case for a prospective trial

The first 10% of the full text of this article appears below.

After the seminal observations of Huggins and Hodges [1] had laid the basis for the hormonal therapy of prostate cancer, Pearson [2] described two patients with castration-resistant prostate cancer that responded to testosterone with relief of symptoms and declines in serum acid phosphatase. The particular molecular context for this seeming paradox . . . [Full Text of this Article]

P. Mathew

Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, 1155 Herman P. Pressler, Houston, TX 77030-3721, USA

(E-mail: pmathew@mdanderson.org)


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