Skip Navigation



Annals of Oncology Advance Access published online on September 13, 2006
Annals of Oncology, doi:10.1093/annonc/mdl307
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
17/12/1842    most recent
mdl307v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Richiardi, L.
Right arrow Articles by Merletti, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Richiardi, L.
Right arrow Articles by Merletti, F.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2006 European Society for Medical Oncology
Received May 8, 2006
Revised July 13, 2006
Accepted July 18, 2006

original article

Occupational exposure to diesel exhausts and risk for lung cancer in a population-based case-control study in Italy

L. Richiardi 1 *, D. Mirabelli 1, R. Calisti 2, A. Ottino 1, A. Ferrando 1, P. Boffetta 3, and F. Merletti 1

1 Unit of Cancer Epidemiology, CeRMS and Centre for Oncologic Prevention, University of Turin, Italy
2 Unit of Occupational Safety and Health, ASUR Marche - Local Department n. 8, Civitanova Marche, Italy
3 Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, Lyon, France

* To whom correspondence should be addressed.
L. Richiardi, E-mail: Lorenzo.Richiardi{at}unito.it


  Abstract

Background: We studied the effect of exposure to diesel exhausts on lung cancer risk in a population-based case-control study in the city of Turin, Italy.

Patients and methods: Information on occupational histories of 595 incident lung cancer cases diagnosed in 1991-1992 and 845 population controls was obtained. During the interviews, diesel job-specific modules (D-JSMs) were administered whenever subjects had worked in occupations included in the following nine categories: railroad workers, miners, professional drivers and transport conductors, heavy-machine operators, mechanics and testers, filling station attendants, motor-vehicle park attendants, transport equipment operators, and occupations carried out in/near urban roads. All D-JSMs were evaluated for probability, intensity and frequency of exposure.

Results: The odds ratio for ever exposure to diesel exhausts was 1.04 (95% confidence interval 0.79-1.37), after adjusting for age, sex, smoking and having worked in occupations entailing exposure to known lung carcinogens. No association was found with intensity, probability and duration of exposure.

Conclusions: Although misclassification of the exposure may have contributed to the negative results, we did not find an association between occupational exposure to diesel exhausts and lung cancer risk.

Keywords: diesel exhausts; lung cancer; occupational exposure; case-control studies; exposure assessment.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.