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Annals of Oncology Advance Access originally published online on September 22, 2009
Annals of Oncology 2009 20(12):2020-2022; doi:10.1093/annonc/mdp457
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© The Author 2009. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

letters to the editor

Rapid progression of hormone receptor-negative breast cancer concomitant with ovarian stimulation—a paradoxon?

The first 10% of the full text of this article appears below.

Fertility preservation in younger cancer patients undergoing adjuvant chemotherapy is gaining importance. Oocyte cryopreservation requires stimulation with gonadotropins, resulting in strong estradiol (E2) increase. There has been concern that this may propagate breast cancer progression, particularly in hormone receptor-positive disease. However, ovarian stimulation is currently considered safe, as a recent study showed that it did not affect recurrence rates during a follow-up of 23 months [1]. Here, we report on a case where ovarian stimulation was . . . [Full Text of this Article]

case report

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disclosure

T. Pukrop1, A. Bleckmann1, A. Einspanier2 and C. Binder1,*

1 Department of Haematology/Oncology, Georg-August-University, Göttingen
2 Institute of Veterinary Physiological Chemistry, University of Leipzig, Germany

* (E-mail: cbinder@med.uni-goettingen.de)


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