Annals of Oncology Advance Access originally published online on September 11, 2009
Annals of Oncology 2009 20(11):1900-1901; doi:10.1093/annonc/mdp448
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© The Author 2009. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org
letters to the editor |
Successful salvage high-dose chemotherapy and autologous stem-cell transplantation in HIV-related germ-cell tumor
| The first 10% of the full text of this article appears below. |
Testicular germ-cell tumors (GCT) occur more frequently in human immunodeficiency virus (HIV)-infected patients than in the general population [1]. Initial studies indicated that the outcome of patients with HIV-related GCT was poor compared with those without HIV infection [2, 3]. Nevertheless, since the introduction of highly active antiretroviral therapy the outcome has improved due to a decrease in HIV-related deaths [4].
Most patients with GCT who achieve a complete response to initial chemotherapy are cured, with relapses occurring
1 Department of Hematology and Oncology, Harlaching Hospital, Academic Teaching Hospital of Ludwig-Maximilians-University
2 Department of Dermatology and Allergology, Ludwig-Maximilians-University
3 Department of Urology, Ludwig-Maximilians-University—Großhadern
4 Department of Medicine, Ludwig-Maximilians-University—Innenstadt
5 Private Practice of Oncology, Munich, Germany
* (E-mail: tumorzentrum.hentrich@khmh.de)