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Annals of Oncology 2008 19(11):1819; doi:10.1093/annonc/mdn704
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© The Author 2008. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

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Node-positive breast cancer is a disease with a significant risk of relapse and death. Anthracycline-containing adjuvant chemotherapy has been shown to increase disease-free survival (DFS) and overall survival. However, breast cancer central nervous system (CNS) metastases are an increasingly important problem because of high CNS relapse rates in patients treated with trastuzumab and/or taxanes. In this issue, Pestalozzi et al. [pp. 1837–1842], . . . [Full Text of this Article]


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