Annals of Oncology 2008 19(11):1819; doi:10.1093/annonc/mdn704
© The Author 2008. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org
in this issue
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CNS relapse related to adjuvant taxane treatment in node-positive breast cancer
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Node-positive breast cancer is a disease with a significant
risk of relapse and death. Anthracycline-containing adjuvant
chemotherapy has been shown to increase disease-free survival
(DFS) and overall survival. However, breast cancer central nervous
system (CNS) metastases are an increasingly important problem
because of high CNS relapse rates in patients treated with trastuzumab
and/or taxanes. In this issue, Pestalozzi et al. [pp. 1837–1842],
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Telomere shortening, DNA damage response and telomeric protein downregulation in colorectal preneoplastic lesions
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CD5 expression as a predictor of outcome in patients with DLBCL receiving rituximab plus CHOP therapy
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Euthanasia, life sustaining treatment and acceleration of death
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