Annals of Oncology Advance Access originally published online on August 9, 2008
Annals of Oncology 2008 19(10):1812-1813; doi:10.1093/annonc/mdn546
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© The Author 2008. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org
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About sorafenib in castration-resistant prostate cancer
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In the study design of Chi et al. [1] is declared that sorafenib would be considered of interest if three or more prostate-specific antigen (PSA) responses were observed in the 25 patients accrued. In their trial, a PSA response occurred in one patient among 28 patients treated with sorafenib; therefore, sorafenib should be considered ineffective in chemonaive castration-resistant prostate
1 Operative Unit of Medical Oncology, Ospedale Civile, Sanremo
2 Operative Unit of Radiotherapy, Città di Castello Hospital, Città di Castello, Italy
* (E-mail: oncologia@katamail.com)
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