Annals of Oncology Advance Access originally published online on August 5, 2008
Annals of Oncology 2008 19(10):1811-1812; doi:10.1093/annonc/mdn547
© The Author 2008. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org
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The anthracyclines and the clinical practice: do all breast cancer patients benefit? Results from the NORA study
| The first 10% of the full text of this article appears below. |
Recent data seem to indicate that only some groups of early breast cancer patients benefit from an adjuvant treatment with anthracyclines [1]. In particular, in HER2-positive disease, anthracyclines are reported to be superior to nonanthracycline regimens in terms of disease-free survival (DFS) and overall survival, independently of the method by which the overexpression or amplification was determined.
Few data are available at the moment about a possible benefit of anthracyclines
1 Department of Medical Oncology, San Gerardo Hospital, Monza
2 Department of Medical Oncology, IST, Genoa
3 Department of Medical Oncology, University of Trieste, Trieste
4 Department of Medical Oncology C, Istituto Pascale, Naples
5 Department of Medical Oncology, Ospedale Careggi, Florence
6 Department of Oncology, Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy
* (E-mail: oncologia@tin.it)