© 2007 European Society for Medical Oncology
letters to the editor |
Liposomal doxorubicin is active in StewartTreves syndrome
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In 1948, Stewart and Treves described some cases of lymphangiosarcoma arised in women who had previously undergone radical mastectomy and axillary node dissection for breast cancer [1]. After this first report, this rare clinical entity has been called StewartTreves syndrome (STS). Following mastectomy, patients affected by STS develop purple-colored multifocal raised cutaneous lesions progressing to ulceration in the lymphoedematous upper limb within a median of 10 years (range: 527 years) [2]. So far,
300 cases of STS have been reported [3]. Lymphonodal dissection complicated by lymphedema has
1 Medical Oncology Unit, University of Magna Græcia and T. Campanella Cancer Center, Campus Germaneto, Viale Europa, 88100 Catanzaro
2 Pathology Unit
3 Breast Unit, "Pugliese-Ciaccio" Hospital, Catanzaro, Italy
* (E-mail: oncologia@unicz.it)