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Annals of Oncology Advance Access originally published online on March 9, 2007
Annals of Oncology 2007 18(4):619-621; doi:10.1093/annonc/mdm071
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© 2007 European Society for Medical Oncology

editorials

Potential risks and benefits of radiation therapy as adjuvant treatment in patients with low-risk carcinoma of the mammary gland: taking cutaneous postradiation angiosarcoma as an opportunity for a critical appraisal of postoperative radiotherapy

J Bernier*

Department of Radio-Oncology, Clinique de Genolier, Genolier Swiss Medical Network, CH-1272 Genolier, Switzerland

* E-mail: jbernier@genolier.net

The first 150 words of the full text of this article appear below.

In this issue of Annals of Oncology, M. Moe and G. Bertelli [1] propose, in a ‘Letter to the Editor', a number of interesting considerations on the clinical pattern and treatment of breast angiosarcoma, with emphasis on a woman presenting this disease after breast-conserving surgery (BCS) and radiotherapy, with a short latent period following her first-line treatment.

Their letter first calls for a number of comments on a typical example of radio-induced late effects, the occurrence of which always represents a source of profound frustration both for the patient and her radiation oncologist.

As an aggressive tumor of endothelial origin, angiosarcoma of the breast (AS) is occurring as idiopathic, lymphedema-associated, postirradiation, soft tissue, and various other clinical settings [1, 2]. Among these settings, iatrogenic AS, also known as ‘Stewart–Treves syndrome’ is usually attributed to chronic lymphedema, which can occur in a number of patients . . . [Full Text of this Article]


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