Annals of Oncology Advance Access originally published online on November 20, 2007
Annals of Oncology 2007 18(12):2042-2043; doi:10.1093/annonc/mdm504
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© 2007 European Society for Medical Oncology
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Triple-negative breast cancer: MRI features in 29 patients
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Triple-negative (TN) breast cancers were defined as those which tested negative for estrogen receptor (ER), progesterone receptor (PR), and HER2. TN breast cancers account for 12%–26% of all types of breast cancers [1–5]. TN tumors were aggressive and were usually diagnosed at a later stage [5]. About 85% of TN phenotypic breast cancers are deemed to be basal like and have a clinical behavior similar to basal-like tumors [2]. The most common histological types for TN breast cancer were invasive ductal carcinomas and metaplastic carcinomas [2]. Histologically, TN cancers are poorly differentiated,
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1 Center for Functional Onco-Imaging, University of California, Irvine, CA, USA
2 Department of Radiology, China Medical University Hospital, Taichung, Taiwan
3 Department of Pathology and Laboratory Medicine
4 Department of Medicine, University of California, Irvine, CA, USA
* (E-mail: jeonhc@uci.edu)
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