© 2007 European Society for Medical Oncology
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Demographic, clinical, and pathological characteristics of Turkish triple-negative breast cancer patients: single center experience
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Triple-negative breast cancers are frequently defined as a single group identifiable using routine clinical tests. They are negative for estrogen receptor (ER), progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER2), the so-called triple-negative breast cancers. This term originated from hierarchical clustering analysis of gene expression microarray studies [1, 2]. One of the five subtypes of breast cancer identified by these analyses characteristically expressed very low levels of ER and related genes and did not have HER2 overexpression, the triple-negative phenotype. This subtype
Department of Medical Oncology, Hacettepe University Institute of Oncology, Ankara, Turkey
* (E-mail: altundag66@yahoo.com)