Skip Navigation


Annals of Oncology Advance Access originally published online on April 27, 2005
Annals of Oncology 2005 16(8):1400; doi:10.1093/annonc/mdi233
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
16/8/1400    most recent
mdi233v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (4)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Shimada, H.
Right arrow Articles by Takahashi, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shimada, H.
Right arrow Articles by Takahashi, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2005 European Society for Medical Oncology

Letter to the Editor

Little response to zoledronic acid in a child of juvenile myelomonocytic leukemia (JMML) harboring the PTPN11 mutation

The first 10% of the full text of this article appears below.

Juvenile myelomonocytic leukemia (JMML) is a clonal myeloproliferative disorder with a high mortality rate. Dysregulation of the RAS pathway has been implicated in the pathogenesis. A targeting therapy against the RAS pathway, therefore, can be an important therapeutic option. Zoledronic acid, a third-generation bisphosphonate that is capable of inhibiting the activation of small GTPases, was . . . [Full Text of this Article]

H. Shimada*, H. Shima, N. Shimasaki, H. Yoshihara, T. Mori and T. Takahashi

Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan

* Email: hshimada@1992.jukuin.keio.ac.jp


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 haematolHome page
C. Flotho, C. P. Kratz, and C. M. Niemeyer
How a rare pediatric neoplasia can give important insights into biological concepts: a perspective on juvenile myelomonocytic leukemia
Haematologica, November 1, 2007; 92(11): 1441 - 1446.
[Full Text] [PDF]