Annals of Oncology 15:987-988, 2004
© 2004 European Society for Medical Oncology
Central nervous system side-effects of 5-HT3-receptor antagonists in elderly cancer patients treated with chemotherapy
1 G. Di Maria Hospital, Medical Oncology, Avola, Siracusa; 2 Centro Catanese di Oncologia, Medical Oncology, Catania, Italy
*E-mail: tralongo.paolo@virgilio.it
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The side-effect profile of supportive treatment is particularly important in the subgroup of elderly patients, as they are susceptible to adverse effects. Such patients may be suffering co-morbidity conditions, taking multiple medications and therefore may be unable to tolerate any further reduction to their quality of life.
Nausea and vomiting are typical side-effects of chemotherapy and also occur in a significant number of patients who are undergoing radiation therapy or surgery. The 5-HT3-receptor antagonists are used for prophylaxis against chemo-