Annals of Oncology 15:847-849, 2004
© 2004 European Society for Medical Oncology
Self-testing for human papillomavirus using a vaginal swab: placing prevention of cervical cancer in the patients hands
Division of Adolescent Medicine, Cincinnati Childrens Hospital Medical Center, The University of Cincinnati College of Medicine, Cincinnati, Ohio, USA. E-mail: jessica.kahn@cchmc.org
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Although the implementation of cervical cytology (Pap) screening has been responsible for a dramatic decline in the incidence of cervical cancer over the past 50 years in developed countries [1], its limitations are evidenced by the fact that cervical cancer remains a leading cause of death among women worldwide [24]. The primary limitation of the Pap test is its low sensitivity for detection of cervical intraepithelial neoplasia (CIN), necessitating frequent screening intervals [5]. Furthermore, many women do not participate in screening programs or adhere to recommendations for follow-up of abnormal results, perhaps because they do not understand the rationale for screening or find the pelvic examination to be painful or embarrassing [68]. In developing countries additional barriers to screening include a lack of trained providers and the infrastructure necessary to perform testing, as well