Annals of Oncology 15:537, 2004
© 2004 European Society for Medical Oncology
Tumor lysis syndrome in a multiple myeloma treated with thalidomide
Department of Medical Oncology, Hospital de Cruces, Plaza de Cruces s/n, Barakaldo 48903, Spain
*E-mail: glvivanco@hcru.osakidetza.net
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A 60-year-old male with progressive high burden non-secretory multiple myeloma (NSMM) presented with tumor lysis syndrome (TLS) after starting thalidomide. He was diagnosed in 1998 with NSMM stage IIIA according to Durie and Salmons classification. Initial treatment consisted of six cycles of vincristine, doxorubicin and dexamethasone (VAD), and double high doses