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Annals of Oncology 14:339-340, 2003
© 2003 European Society for Medical Oncology

Letters to the Editor

Amelioration of docetaxel/cisplatin induced polyneuropathy by {alpha}-lipoic acid

C. Gedlicka, G. V. Kornek, K. Schmid and W. Scheithauer*

Clinical Division of Oncology, Department of Internal Medicine I, University of Vienna, Vienna, Austria

*E-mail: werner.scheithauer@akh-wien.ac.at

The first 10% of the full text of this article appears below.

Docetaxel (Taxotere®; Aventis, Strasbourg, France) is currently considered to be one of the most important anticancer drugs. It is a semi-synthetic agent derived from baccatin III extracted from renewable Taxus baccata needles, which binds to tubulin inducing its polymerization [1]. It inhibits cell replication and leads to apoptosis. Docetaxel has displayed significant antitumor activity against non-small-cell lung cancer (NSCLC), head and . . . [Full Text of this Article]


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