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Annals of Oncology 14:1587-1588, 2003
© 2003 European Society for Medical Oncology

Letters to the Editor

Anastrozole and quinapril can be safely coadministered to elderly women with breast cancer and hypertension: a pharmacokinetic study

L. Repetto*,1,2, O. Vannozzi3, A. Hazini2, A. Sestini4, M. Pietropaolo4 and R. Rosso2

1 Oncology Unit INRCA, Rome; 2 Oncology Unit IST, Genoa; 3 Pharmacology IST, Genoa; 4 Geriatric Department "La Sapienza", University of Rome, Rome, Italy

*E-mail: l.repetto@inrca.it

The first 10% of the full text of this article appears below.

Concomitant use of hormone therapy and antihypertensive therapy in elderly women is compelled by a high prevalence of breast cancer with hypertension [1]. However, very little is known about the possible interaction of combined treatment and older patients represent a high-risk group due to declining renal function and liver metabolism. Previous research into the effect of aromatase enzyme activity using angiotensin-converting enzyme (ACE) inhibitors has been predominantly carried out on animal . . . [Full Text of this Article]


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