Annals of Oncology 14:170, 2003
© 2003 European Society for Medical Oncology
Letters to the Editor |
Comment on "A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer", by C. M. Rudin et al. (Ann Oncol 2002; 13: 539545)
1 Division of Medical Oncology, University Hospital, Bern; 2 Division of Medical Oncology, University Hospital, Zürich, Switzerland
*E-mail: oliver_gautschi@hotmail.com
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In their pilot study, Rudin et al. describe the safety, feasibility and toxicity profile of the combination of paclitaxel and G3139 (GenasenseTM), a bcl-2 antisense oligonucleotide, in patients with chemoresistant small-cell lung cancer (SCLC). Tolerance