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Annals of Oncology 13:343-344, 2002
© 2002 European Society for Medical Oncology

Editorial

Is pharmacokinetically guided chemotherapy dosage a better way forward?

J. Bergh

Professor of Clinical and Molecular Oncology, Cancer Centre Karolinska and Radiumhemmet Karolinska Institute and Hospital, Stockholm, Sweden

Chemotherapy is one of the corner stones of the present cancer therapy arsenal. Selection of drugs, combinations and schedules is frequently based on group statistics data, ideally from controlled studies. The antitumoural effects of the cytostatics have to be carefully balanced against their well-known side effects.

In the future, the selection of drugs and their combinations should be based on the individual analyses of relevant tumour biological factors and pharmacokinetic parameters aiming at a truely tailored . . . [Full Text of this Article]

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