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Annals of Oncology 13:16-18, 2002
© 2002 European Society for Medical Oncology

Editorial

Faecal occult blood testing (FOBT) as screening for colorectal cancer: the current controversy

P. Boyle

Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy

Colorectal cancer is the fourth most common form of cancer that occurs worldwide, with an estimated 782 900 new cases diagnosed in 1990 [1]. The disease is not uniformly fatal, although there are large differences in survival according to the stage at which the disease is detected. In advanced colorectal cancer in which curative resection is possible, 5-year survival in Dukes’ B is 45%, dropping to 30% in Dukes’ C [2]. Five year survival in resected Dukes’ A is ~80% and survival following simple resection of an adenomatous pedunculated polyp containing carcinoma in situ (or severe dysplasia) or intramucosal carcinoma is generally close to 100%. Although it has been argued that death from colorectal cancer may be avoidable [3], it is estimated that there are still 394 000 deaths from colorectal cancer annually worldwide [4].

The identification of a well-defined pre-malignant lesion, . . . [Full Text of this Article]

Acknowledgements

References


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