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Table 2. Studies with standard and extended rituximab dose in WM, including this study by the Waldenstrom's Macroglobulinemia Clinical Trials Group (WMCTG)

N Median no. of infusions Major RR Response duration

Byrd et al. [7] 6 4 57% 6.6+ months
Treon et al. [8] 30 4 27% 8.4 months
Weber et al. [9] 8 4 75% 9.0 months
Foran et al. [10] 7 4 29% NA
Gertz et al. [11] 69 4 27% 27+ months
Dimopoulos et al. [13] 27 8 44% 16+ months
WMCTG 29 8 48% 29+ months

Major response rate (RR) reflects percentage of patients achieving partial and complete responses only.





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