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Annals of Oncology 2004 15(12):1848-1849; doi:10.1093/annonc/mdh481
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© 2004 European Society for Medical Oncology

Solid tumors in patients treated for Hodgkin's disease

We read with interest the article by Behringer et al. published in Annals of Oncology. They retrospectively analyzed patients with Hodgkin's disease for secondary solid tumors following treatment of Hodgkin's disease. They reported that lung cancer (23.6%) and colorectal cancer (20.5%) were the most common solid tumors in long-term survivors after the treatment of Hodgkin's disease [1Go].

Smoking and alcohol consumption are risk factors for the development of many solid tumors such as lung, larynx, pharynx, oral cavity, colon, esophagus, kidney, pancreas, breast and cervix cancer [2Go–4Go]. Smoking- and alcohol-related cancers constitute approximately 63% of secondary cancers reported in Behringer et al.'s study, but the prevalence of smoking and alcohol consumption was not reported in that study. To make a firm conclusion, the study population should have been analyzed according to the risk factors in the development of solid tumors.

G. Utkan*, A. Büyükçelik and B. Yalçin

Department of Medical Oncology, Ankara University School of Medicine, 06100-TR, Sihhiye, Ankara, Turkey

* Email: gungorutkan_md{at}yahoo.com

References

1. Behringer K, Josting A, Schiller P et al. Solid tumors in patients treated for Hodgkin's disease: a report from the German Hodgkin Lymphoma Study Group. Ann Oncol 2004; 15: 1079–1085.[Abstract/Free Full Text]

2. Hamajima N, Hirose K, Tajima K et al. Alcohol, tobacco and breast cancer—collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer 2002; 18: 1234–1245.

3. Koh KH, Kannler C, Geller CA. Cancer prevention: preventing tobacco related cancers. In De Vita VT Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology, 6th edition. Philadelphia, PA: Lippincott Williams and Wilkins 2001; 550.

4. Cho E, Smith-Warner SA, Ritz J et al. Alcohol intake and colorectal cancer: a pooled analysis of 8 cohort studies. Ann Intern Med 2004; 140: 603–613.[Abstract/Free Full Text]


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This Article
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