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Annals of Oncology 2009 20(Supplement 4):iv37-iv40; doi:10.1093/annonc/mdp123
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© The Author 2009. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

ESMO clinical recommendations

Pancreatic cancer: ESMO Clinical Recommendations for diagnosis, treatment and follow-up

S. Cascinu1, S. Jelic2 and On behalf of the ESMO Guidelines Working Group*

1 Department of Medical Oncology, Università Politecnica delle Marche, Ancona, Italy
2 Internal Medicine Service, Institute of Oncology and Radiology, Belgrade, Serbia

* Correspondence to: ESMO Guidelines Working Group, ESMO Head Office, Via L. Taddei 4, CH-6962 Viganello-Lugano, Switzerland; E-mail: clinicalrecommendations@esmo.org

The first 150 words of the full text of this article appear below.


    incidence
 
In Europe, cancer of the pancreas is the 10th most frequent cancer, accounting for some 2.6% of cancer in both sexes, and the eighth leading cause of cancer-related death with ~65 000 deaths each year. In men, the annual incidence rates ranged between 8.7 (East) and 7.3 (North and West) per 100 000, while in women between 5.7 (North) and 4.5 (East). Men have an approximately one-half greater age-adjusted incidence rate than women. Incidence increases steeply with age from 1.5 per 100 000/year in patients 15–44 years old to 55 per 100 000/year in patients >65 years of age. Pancreatic cancer is one of the most highly fatal cancers, with >95% of those affected dying of their disease.


    diagnosis
 
Histologically there are three types of pancreatic cancer. Infiltrating . . . [Full Text of this Article]


    staging and risk assessment
 

    treatment plan
 
stage I
stage IIA
stage IIB and III
stage IV
palliative therapy

    response evaluation and follow-up
 

    note
 

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