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Annals of Oncology 2009 20(Supplement 4):iv34-iv36; doi:10.1093/annonc/mdp122
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© The Author 2009. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

ESMO clinical recommendations

Gastric cancer: ESMO Clinical Recommendations for diagnosis, treatment and follow-up

C. Jackson1, D. Cunningham1, J. Oliveira2 and On behalf of the ESMO Guidelines Working Group*

1 Gastrointestinal Unit, Royal Marsden Hospital, Sutton, UK
2 Service of Medical Oncology, Portuguese Institute of Oncology, Lisbon, Portugal

* Correspondence to: ESMO Guidelines Working Group, ESMO Head Office, Via L. Taddei 4, CH-6962 Viganello-Lugano, Switzerland; E-mail: clinicalrecommendations@esmo.org

The first 10% of the full text of this article appears below.


   incidence
 
Although the incidence of gastric cancer is decreasing, there were still 159 900 new cases in Europe in 2006, and ~118 200 deaths, representing the fifth highest incidence and fourth highest cause of cancer-related death. The peak incidence is in the seventh decade, and the male:female ratio exceeds 1.5. There is marked geographic variation. Risks include male gender, cigarette smoking, Helicobacter pylori infection, atrophic gastritis, partial gastrectomy, Menetrier's disease and genetic factors such as hereditary non-polyposis colorectal cancer, familial adenomatous polyposis, hereditary diffuse gastric cancer and Peutz–Jeghers syndrome.


   diagnosis
 
Diagnosis should be made from a gastroscopic or surgical biopsy reviewed by an experienced pathologist, and histology . . . [Full Text of this Article]


   staging
 

   treatment plan
 
treatment of localized disease
treatment of metastatic disease

   follow-up
 

   note
 

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