© The Author 2009. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org
ESMO clinical recommendations |
Endometrial carcinoma: ESMO Clinical Recommendations for diagnosis, treatment and follow-up
1 Department of Gynecological Oncology, The Norwegian Radium Hospital, Oslo, Norway
2 Institute of Social and Preventive Medicine (ISPM), University of Geneva, Geneva, Switzerland
* Correspondence to: ESMO Guidelines Working Group, ESMO Head Office, Via L. Taddei 4, CH-6962 Viganello-Lugano, Switzerland; E-mail: clinicalrecommendations@esmo.org
| The first 10% of the full text of this article appears below. |
| incidence |
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The crude incidence of endometrial carcinoma in the European Union is 16 cases/100 000 women/year (range 13–24). The mortality is 4–5 cases/100 000/year. The lifetime risk of developing endometrial carcinoma is
1.7–2%, and age-standardized incidence rates continue to rise in most developed countries.
| diagnosis |
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The diagnosis of endometrial carcinoma requires histopathological confirmation. This diagnosis is made according to the WHO pathological classification. About 80% of endometrial carcinomas are of endometrioid type. Serous (5–10%), clear cell (1–5%), mucinous, mixed, squamous cell, transitional cell
| staging and risk assessment |
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degree of differentiation:
| treatment plan |
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stage I
stage II
stages III and IV
| follow-up |
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| note |
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