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Annals of Oncology 2009 20(Supplement 4):iv24-iv26; doi:10.1093/annonc/mdp118
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© The Author 2009. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org

ESMO clinical recommendations

Non-epithelial ovarian cancer: ESMO Clinical Recommendations for diagnosis, treatment and follow-up

N. Colombo1, M. Peiretti1, M. Castiglione2 and On behalf of the ESMO Guidelines Working Group*

1 Department of Gynecologic Oncology, European Institute of Oncology, Milan, Italy
2 Institute of Social and Preventive Medicine (ISPM), University of Geneva, Geneva, Switzerland

* Correspondence to: ESMO Guidelines Working Group, ESMO Head Office, Via L. Taddei 4, CH-6962 Viganello-Lugano, Switzerland; E-mail: clinicalrecommendations@esmo.org

The first 10% of the full text of this article appears below.


   incidence
 
Non-epithelial malignancies of the ovary account for ~10% of all ovarian cancers. Germ cell tumors (GCTs) are diagnosed principally in young subjects whereas sex cord stromal tumors (SCSTs) are more common in adult women. GCTs represent 5% of all ovarian neoplasms and 80% of preadolescent malignant ovarian tumors. Sex cord stromal tumors are rare neoplasms that account for ~3–5 % of ovarian malignancies and for the majority are functioning tumors with clinical manifestations. The yearly adjusted incidence rate is 3.7/1000 000 and 2.1/1000 000 women for GCTs and SCSTs, respectively.


   diagnosis
 
The initial symptoms and signs of non-epithelial ovarian cancers are usually characterized by subacute pelvic . . . [Full Text of this Article]


   staging and risk assessment
 

   treatment plan
 
early stage disease, FIGO stage I–IIa
germ cell tumors.
sex cord stromal tumors.
advanced stage disease, FIGO stage IIb–IV
germ cell tumors.
sex cord stromal tumors.

   response evaluation
 

   follow-up
 

   note
 

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