Annals of Oncology 2006 17(8):1179; doi:10.1093/annonc/mdl293
© 2006 European Society for Medical Oncology
in this issue
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Extranuclear hormone receptors in primary breast cancer
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Proliferation of breast cancer cells is divided into hormone-dependent
and -independent tumor growth; the former is regulated by the
expression of hormone receptors (HRs) such as estrogen (ER)
and progesterone receptors (PR). Estrogens such as estradiol
are a crucial growth factor for HR-positive breast cancer cells,
with growth stimulation being mediated by the genomic action
of nuclear ERs. In contrast, extranuclear ER expressed in the
cell membrane and cytoplasm
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Survival differences for bronchioloalveolar carcinoma patients
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Mast cells in Waldenstrom's macroglobulinemia support lymphoplasmacytic cell growth
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Colorectal cancer screening using sigmoidoscopy
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