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Annals of Oncology 2005 16(12):1851; doi:10.1093/annonc/mdi412
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© 2005 European Society for Medical Oncology

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The first 10% of the full text of this article appears below.


   Lung adenocarcinoma biomarkers—differences between smokers and never-smokers
 
Non-small-cell lung cancer (NSCLC) arising in never-smokers is usually of adenocarcinoma subtype, but the oncogenesis of such tumors is poorly understood. Tumors from never-smokers often arise in a focal manner and are less frequently associated with gene mutations, loss of heterozygosity, chromosomal abnormalities and DNA methylation than tobacco-related lung tumors. Despite these differences that could signify specific genetic alterations, the treatment of NSCLC has not generally taken the tobacco status of patients into consideration. One major . . . [Full Text of this Article]


   Effects of trastuzumab on ovarian cancer
 

   Darbepoetin-alfa in myelodysplatic syndromes
 

   Parent–adolescent communication in the case of parental cancer
 

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