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Annals of Oncology 15:375-381, 2004
© 2004 European Society for Medical Oncology

Metastases to the heart

K. Reynen*, U. Köckeritz and R. H. Strasser

Department of Internal Medicine II, University of Dresden, Heart Center Dresden, Dresden, Germany

Received 11 August 2003; revised 6 September 2003; accepted 17 September 2003

The first 150 words of the full text of this article appear below.

Primary tumors of the heart are rare, occurring at a frequency of ~0.02% in pooled autopsy series [1]. Histologically, three-quarters of primary heart tumors turn out to be benign, almost half of them being myxomas [2]. Whether benign or malignant, the majority of primary cardiac tumors are intracavitary and preferentially develop in the left atrium, thereby leading to left ventricular inflow obstruction. Embolism is also common. Secondary or metastatic heart tumors occur comparatively more frequently, with an at least 100 times higher incidence than primary tumors of the heart [3]. Intracavitary growth of secondary heart tumors, however, is unusual. Therefore, despite their frequency, metastatic heart tumors only rarely gain clinical attention. However, signs of cardiac involvement are often overlooked, since the symptoms of disseminated tumor disease prevail. Thus, like primary tumors of the heart, metastases may imitate valvular heart disease or cause cardiac failure, . . . [Full Text of this Article]

Definition

Incidence

Tumors of origin

Morphology and topography

Metastatic pathways

Symptomatology

Diagnosis

Differential diagnosis

Treatment

Summary

Acknowledgements


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