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Annals of Oncology 2004 15(10):1450-1451; doi:10.1093/annonc/mdh408
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© 2004 European Society for Medical Oncology

Assessing prognosis in patients with chronic lymphocytic leukemia a quarter of a century after Rai and Binet staging systems

E. Montserrat*

Institute of Hematology and Oncology, Department of Hematology, Hospital Clínic, Villarroel, 170, 08036 Barcelona, Spain

* Email: emontse@clinic.ub.es

The first 10% of the full text of this article appears below.

Chronic lymphocytic leukemia (CLL) has an extremely heterogeneous prognosis. Nowadays, the median survival of patients with this form of leukemia is 8–10 years, compared with 5–6 years in series reported in the 1970s. This is largely due to the higher number of patients who are now being diagnosed in early phase (up to 80%) and, hence, with better prognosis [1Go, 2Go]. Individual survival, however, is highly variable.

 Classically, clinical stages have been used to predict the behavior of the disease [3Go, 4Go]. Although easy . . . [Full Text of this Article]


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