Annals of Oncology 14:505-507, 2003
© 2003 European Society for Medical Oncology
Editorial |
Can anything be done about oral mucositis?
| The first 10% of the full text of this article appears below. |
Oral mucositis continues to afflict most patients who are given chemotherapy with or without total body irradiation to prepare them for a haematopoietic stem cell transplant from peripheral blood or bone marrow. Besides the discomfort and pain caused, the intake of food and fluids can be severely curtailed, leading to dehydration and malnutrition, the risk of infection is increased, and there may even be a risk of other more serious complications such as hepatic veno-occlusion [1]. Throughout the last two decades there have been many attempts to identify remedies to prevent or at least ameliorate oral mucositis [2], but with mixed results. Moreover, the targets for these interventions have varied from bland rinses to growth