Annals of Oncology 13:35-39, 2002
© 2002 European Society for Medical Oncology
Debate |
Faecal occult blood testing for colorectal cancer
University Department of Surgery, Royal Infirmary, Glasgow, UK
Received 9 August 2001; accepted 10 October 2001.
Key words: colorectal cancer, faecal occult blood, screening
Rationale for screening
Colorectal cancer is the second most common cause of death from cancer in the western world. Each year there are almost 800000 new cases and over 400000 deaths attributable to the disease worldwide. In the UK alone, there are more than 32000 new cases and over 17000 deaths each year [1]. The incidence has increased by ~1% per year over the last 25 years in men, but rates in women have hardly changed. Recently, mortality has fallen (Table 1). For example, between 197175 and 198690, 5-year relative survival for colorectal cancer in England and Wales increased from approximately 27% to 39% [2]. Similar increases in 5 year relative survival have been observed in Scotland [3]. It is not clear from these registry-based data whether the improvement in survival is due to earlier presentation or improvements in treatment.
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Faecal occult blood testing
The Minnesota study
The Nottingham study
The Scandanavian studies
Flexible sigmoidoscopy
Conclusion
Footnotes
References
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