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Annals of Oncology 9:S87-S90, 1998
© 1998 European Society for Medical Oncology

Reviews

Radiation therapy as a component of high-dose salvage strategies in Hodgkin's disease

R. T. Hoppe

Department of Radiation Oncology. Stanford University Stanford, CA, USA

Correspondence to: R.T Hoppe. MD Department of Radiation Oncology, Room AO77 Stanford University Stanford. CA 94305 USA

The expected event-free survival for patients undergoing high-dose salvage therapy for Hodgkin's disease is 40%–60%. Three-quarters of these patients will relapse in prior sites of disease. Radiation therapy is a very effective local-regional modality in Hodgkin's disease. It is possible that the judicious use of radiation can improve the event-free survival of high-dose salvage programs. Retrospective analysis supports this concept, but the rationale should be incorporated and tested in prospective clinical trials.

high-dose chemotherapy, Hodgkin's disease, radiation therapy, salvage therapy


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