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Annals of Oncology 9:S121-S123, 1998
© 1998 European Society for Medical Oncology

Reviews

Treatment of grey zone lymphomas

R. I. Fisher

Cardinal Bernardm Cancer Center, Loyola University Medical Center Maywood. IL, USA

Cardinal Bernardin Cancer Center, Chairman. Lymphoma Committee. Southwest Oncology Group Loyola University Medical Center, 2160 South First Avenue Maywood. IL 60153 USA

The inability of distinguishing difficult cases of Hodgkin's disease from non-Hodgkin's lymphoma has been a long-standing problem. Initially, the controversy centered on lymphocyte-depleted Hodgkin's disease; now with improved diagnostic techniques, most controversy centers around the anaplastic large-cell lymphomas. These problematic cases may also represent a less frequent problem, although data on this point is difficult to obtain. The future controversy may well involve the separation of T-cell rich B-cell lymphoma and Hodgkin's disease, nodular paragranuloma type. Fortunately, to date the clinical data does not support that there is a major difference in therapeutic results depending on whether these cases are treated as Hodgkin's disease or non-Hodgkin's lymphoma.

grey zone lymphoma, Hodgkin's, disease, non-Hodgkin's lymphoma


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