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Annals of Oncology 8:S29-S32, 1997
© 1997 European Society for Medical Oncology

Primary B-cell lymphomas of the skin

H. Kerl and L. Cerroni

Department of Dermatology, University of Graz Austria

Correspondence to: H. Kerl, MD Department of Dermatology University of Graz Auenbruggerplatz, 8 A-8036 Graz Austria

Primary B-cell lymphomas of the skin are not as rare as is generally believed. They are definedas malignant B-cell proliferations presenting with cutaneous involvement alone and no evidence of extracutaneous manifestations over a period of at least six months when complete staging has been performed. The major subtypes are follicle center-cell lymphoma of the head and trunk, immunocytoma and large B-cell lymphoma of the leg (EORTC classification 1996). Also of interest is the recently recognized marginal-zone B-cell lymphoma. Primary B-cell lymphomas of the skin differ significantly from nodal lymphomas. Awareness of their special clinical behavior should prevent unnecessarily aggressive treatment.

diagnosis, major subtypes, primary cutaneous B-cell lymphomas, treatment


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