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Annals of Oncology 2:765-766, 1991
© 1991 European Society for Medical Oncology


other

Short report: Phase II trial of oral carmofur in advanced pancreatic carcinoma

M. J. Kajanti and S. O. Pyrhonen

Department of Radiotherapy and Oncology, Helsinki University Central Hospital Helsinki, Finland

Correspondence to: Mikael Kajanti, M.D. Department of Radiotherapy and Oncology, Helsinki University Central Hospital, Haartmaninkatu 4, SF-00290 Helsinki, Finland

Thirty-one patients with advanced carcinoma of the pancreas and with no prior exposure to chemotherapy were treated with HCFU. This drug was administered orally at a dose of 300–500 mg/m2 in 6-week cycles with a 2-week interval between the cycles. One partial response was observed and 7 patients showed stable disease. The median survival of the 31 patients was 8.3± 5.4 months (range 1.3–20.3 months). The toxicity was moderate.

pancreas carcinoma, oral carmofur


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