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Annals of Oncology 12:1757-1759, 2001
© 2001 European Society for Medical Oncology

other

Carcinomatous meningitis as a clinical manifestation of pancreatic carcinoma

A. F. Ferreira Filho1,, F. Cardoso1, A. Di Leo1, A. Awada1, V. D. da Silva2, R. B. Tovar2 and G. Schwartsmann2

1 Chemotherapy Unit, Jules Bordet Institute Brussels, Belgium
2 South American Office for Anticancer Drug and Development, Ulbra University Porto Alegre, Brazil

A. F. Ferreira Filho, MD. PhD, Chemotherapy Unit. Jules Bordet Institute, Boulevard de Waterloo 125, Bruxelles 1000, Belgium, E-mail fabiano.ferreira{at}bordet.be

Carcinomatous meningitis (CM) is clinically less common than brain metastasis or spinal cord compression, having dire consequences for both the quality of life and the overall survival of patients with solid tumors. It occurs in about 5% of all adult cancer patients, but autopsies may double this number. If leukemia and lymphoma are excluded, most cases are due to breast cancer, lung cancer and melanoma. In this report, we describe a 49-year-old male patient with metastatic pancreatic adenocarcinoma who developed carcinomatous meningilis. To our knowledge, this is only the second case of carcinomatous meningitis secondary to a pancreatic carcinoma described so far.

carcinomatous meningitis, pancreatic carcinoma


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