Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (6)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Kruit, W. H. J.
Right arrow Articles by Stoter, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kruit, W. H. J.
Right arrow Articles by Stoter, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Annals of Oncology 11:1501-1502, 2000
© 2000 European Society for Medical Oncology

other

Interferon-{alpha} induced Raynaud's syndrome

W. H. J. Kruit1,, A. M. M. Eggermont2 and G. Stoter1

1Department of Medical Oncology, Rotterdam Cancer Institute/University Hospital Rotterdam Rotterdam, The Netherlands
2Department of Surgical Oncology, Rotterdam Cancer Institute/University Hospital Rotterdam Rotterdam, The Netherlands

Correspondence to: W. H. J. Kruit, MD, PhD Department of Medical Oncology Rotterdam Cancer Institute/University Hospital Rotterdam Groene Hilledijk 301 3075 EA Rotterdam The Netherlands E-mail: kruit{at}onch.azr.nl

The cytokine interferon-alpha (IFN-{alpha}) is increasingly prescribed for a number of indications, especially viral hepatitis and several malignancies. Two patients are described who developed Raynaud's syndrome during treatment with IFN-{alpha} as adjuvant therapy for high-risk melanoma. With a review of the available literature the symptomatology, possible pathophysiologic mechanisms and treatment options are discussed.

cytokine, immunotherapy, melanoma, vasospasm


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.