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Annals of Oncology 10:345-350, 1999
© 1999 European Society for Medical Oncology

other

Management of cancer in pregnancy: A case of Ewing's sarcoma of the pelvis in the third trimester

O. Merimsky, T. Le Chevalier, G. Missenard, C. Lepechoux, I. Cojean-Zelek, B. Mesurolle and A. Le Cesne

Unit of Bone and Soft Tissue Sarcoma, Institut Gustave Roussy Villejuif, France

A. LeCesne, MD, Departement de Medecine, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94800 Villejuif, France

Ewing's sarcoma of the pelvic bones was diagnosed in a 21-year childbearing woman, raising major medical and ethical problems. The diagnostic and therapeutic approaches during the sixth month of gestation were tailored in order to cure the patient and avoid unnecessary toxicity to the fetus. Ancillary tests included ultrasound and MRI studies of the pelvis. Ifosfamide and adriamycin, premedicated by granisetron, were administered during gestation, and were found to be safe. Cesarean section was the preferred way of delivery since the tumor involved the pelvic bones. The outcome was a disease-free patient and a small healthy baby who is now two years of age.

chemotherapy, Ewing's sarcoma, pregnancy


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